Yes you may, if you intend on using an FM modulator. The oem system will not interface with your Kenwood changer. But by running it through the antenna lead, you may use that changer. If all you have is the a direct connect DIN plug, you need an FM modulator. The Kenwood part is KCAR-FM I believe, and runs about $60-80. Keep in mind the sound quality is not CD, but rather the best possible FM reception possible.